Internal Medicine Research – Open Journal (ISSN: 2771-800X)

Internal Medicine Research – Open Journal (ISSN: 2771-800X)

Internal Medicine Research – Open Journal, is an International, online journal to expedite rapid publication and to introduce unique innovations and discoveries in basic and clinical sciences of Internal medicine. It was founded by a group of scientists for medical research and clinical scholarly doctors from around the world, who are devoted to the promotion and advancement of our understanding of the diseases and their treatments. The journal essences on advancing therapeutic sciences produced from basic sciences, clinical, and research group or general well being exploration to coordinate looks into in all parts of human well being. In this regard the journal publishes unique & inventive scientific articles, editorials, discussions, advancements, current innovations in internal medicine and other information relevant to internal medicine and related fields.

The scope of the journal includes clinical medicine, epidemiology, prevention, health care delivery, curriculum development, internal medicine, cardiology, clinical immunology, clinical pharmacology, endocrinology, gastroenterology, geriatrics, haematology, contagious diseases, oncology, nephrology, neurology, nuclear medicine, palliative medicine, respiratory medicine and rheumatology.

You are welcome to submit your work to submissions@researchopenworld.com

Open Access Policy: This journal is an open access journal which provides immediate, worldwide, boundary free access to the full content of every distributed article without charging readers or their institutions for access. Readers are given authorization to read, circulate, copy, print, download, search, or link to the full texts of all articles in IMROJ.

Editorial Board

Editors In Chief

Prof. Giuseppe Murdaca, Ph.D.
Expertise in Immunology,
Department of Internal Medicine,
University of Genova,
ITALY

Adel Ekladious
Senior consultant and Professor of Medicine
Bunbury Regional Hospital
University of Western Australia
Australia

Dr.Amr Edrees, M.D.

Specialization in Rheumatology,
Internal Medicine,University of Missouri,
Kansas City,
USA


Prof. Federico Cacciapuoti

Department of Internal Medicine,
Faculty of Medicine,
Second University of Naples,Naples,
ITALY


Dr.Francesco Bellanti

Hepatology,
Internal Medicine (General Medicine),
University of Foggia,Foggia,
ITALY


Dr.Burak Uz, MD

Gazi University Faculty of Medicine,
Department of Internal Medicine,
Division of Adult Hematology, Ankara,
Turkey


Dr.Gaurav K.Sharma, MD

The Department of Internal Medicine,
Mercy Hospital and Medical Center,
Chicago,
USA


Dr.Chaddha Ashish

Department of Internal Medicine,
University of Wisconsin Hospital and Clinics,Madison,
USA


Prof. Monica Lamberti

Second University of Naples,
Caserta,
Campania,
ITALY


Dr.Rahul Vasudev, Ph.D.

New York Medical college,
St Joseph’s Regional Medical Center,
New Jersey,
USA


Prof. Yoshitaka Fukuzawa

Professor and Director,
Preemptive and Integrative Medicine Center,
Aichi Medical University &
Aichi Medical Hospital,
Japan

Prof. Chung-Yi Chen

Dean and Professor,
School of Medical and Health Sciences,
Fooyin University, Taiwan,
CHINA


Dr.Fadi Haddad

Department of Internal Medicine,
Staten Island University Hospital/Northwell Health,Staten Island,NY,
USA


Prof. Massimo Ciccozzi

International Education, Didactics, Adult Education,
Department of Infectious Diseases,
Italian National Institute of Health, Rome,
ITALY


Dr.Luigi Pagliaro

Professor Emeritus of Internal Medicine,
University of Palermo,
Palermo,
ITALY


Dr.Mahir Cengiz ,MD

Internal Medicine
(General Medicine),
University of Istanbul,Istanbul,
Turkey


Dr.Shadi Hamdeh

Creighton University School of Medicine,
Department of Internal Medicine,
Omaha, NE,
USA


Dr.Sumru Savas

Ege University,
Department of Internal Medicine,
Section of Geriatrics,Izmir,
Turkey


Dr.Katherine S Blondon, Ph.D.

Division of General Internal Medicine,
Geneva University Hospitals,
Geneva,
Switzerland

Dr.Wei-Gang Hu

Bio-Threat Defence Section,
Defence Research & Development Canada,
Suffield Research Centre,
Canada


Dr.Theodosios Filippatos ,MD,PHD

Department of Internal Medicine,
School of Medicine,
University of Loannina,Loannina,
Greece


Dr.Moses Elisaf

Professor of Medicine,
Director of the Second Department of Internal Medicine,University of Ioannina,
Greece


Dr.Nilay Patel

Internal Medicine Department,
Saint Peter’s University Hospital,
New Brunswick,NJ,
USA


Dr.Antonio Simone Laganà, M.D.

Unit of Gynecology and Obstetrics,
Department of Human Pathology in Adulthood and Childhood “G. Barresi”,University of Messina,
ITALY


Dr.Leonardo Roever

Department of Clinical Research,
Federal University of Uberlandia(UFU),
Uberlandia,
Brazil


Prof. Essam Ahmed Al-Moraissi

Department of Oral and Maxillofacial Surgery,
Faculty of Dentistry,
Thamar University,
Republic of Yemen


Dr.ITIR Yegenaga

Department of Internal Medicine,
Kocaeli University Medical School,
Kocaeli,
Turkey

Published Articles

Bilateral Optic Neuropathy Induced by COVID-19

MusaYiğit

Case Report – Internal Med Res Open J

DOI: 10.31038/IMROJ.2023812

Can Modern Medicine have Distorted Ideas?

Igor Klepikov MD

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2023811

Metformin Use and Mortality among Prostate Cancer Patients

Huan-ju Shih, Hua Min, Janusz Wojusaik and Panagiota Kitsantas

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021654

Inguinal Hernias Repair by Laparascopy (TEP)

Olga Caridad León González, Pedro Rolando López Rodríguez, Lais Angélica Ceruto Ortiz, Jorge Agustín Satorre Rocha, Eduardo García Castillo, et al.

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021653

Alcohol and Health: Social Evolution, Production and Control

Paul Durrington and Handrean Soran

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021652

From Evolutionary Medicine to Precision Medicine in the Hypertension Treatment in Africa

Ângela Inácio, Laura Aguiar and Manuel Bicho

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021651

Effects of Radiation on Mitochondrial Defective Lymphoblastoid Cells

Jessica Chen, Deepa Sridharan, Chad Cross and Janice Pluth

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021643

How are Vitamin B12 and S-Adenosylmethionine Related?

Perry Allen Frey

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021642

Ovarian Cystadenocarcinoma with an Osteosarcoma Component

Pr S Sakhri esp Boulhart

Case Report – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021641

The Impact of Culture and Beliefs in Cancer Care: Turkish Experience

Sedat Ozkan

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021616

The Organization of the Dental Service in the Voronezh Region

Antonenkov Yu E

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021613

Double-Blind Testing of the Lifewave X39 Patch to Determine GHK-Cu Production Levels

Caitlin A Connor, Melinda H Connor, David Yue, Jens Eickhoff, Susan Wagner and Amy Chang

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021612

Tissue Infiltration of Tumor-Associated Macrophages: Towards the Identification of Therapeutic Targets

Thibaut Sanchez, Frédéric Lagarrigue and Véronique Le Cabec

Short Commentary – Internal Med Res Open J

DOI: 10.31038/IMROJ.2021611

Health Care Provider’s Knowledge on Snakes and Snakebites – A Study in the Three Tongu Districts of the Volta Region, Ghana

Evans Paul Kwame Ameade, Isaac Bonney and Evans Twumasi Boateng

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2020534

Disease, Duration and Death

Narayan Bahadur Basnet

Short CommunicationInternal Med Res Open

DOI: 10.31038/IMROJ.2020533

Personalised Approaches in Treating Early-Stage Hodgkin Lymphoma

Tim Illidge and Elizabeth H Phillips

Editorial CommentaryInternal Med Res Open J

DOI: 10.31038/IMROJ.2020531

An Uncommon Cause of Bilateral Pulmonary Nodules in a Long-Term Smoker

Alameeri Amel, Lane Stephen, Mohammed Nur Mutaz, Loftus Barbara and Hogan Brenden

Case ReportInternal Med Res Open J

DOI: 10.31038/IMROJ.2020512

SARS-Cov2: A Review of this Novel Coronavirus

Dominic Worku and Elliott Worku

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2020511

Blood Transfusion Guided by Physiological Markers

Mario A Rodríguez Domínguez, Ana Maria Espinosa-Galindo, Luis Javier Marfil-Rivera and Dionisio Palacios-Ríos

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019425

Urinary Prothrombin Fragment 1 + 2 as an Endogenous Marker of Venous Thromboembolism

Fredrik Wexels, Walter Jeske, Ola E. Dahl and Jawed Fareed

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019424

First Case Report of Pancreatitis in Lyme disease

A Baisse, S Parreau, A Abdeh and N Pichon

Case Report – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019423

Thoughts at a White Coat Ceremony

Robert T. Means, Jr.

Perspective Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019422

Occupational Performance of Children and Adolescents with Mucopolysaccharidosis Using Assistive Technologies

Luana Ramalho Jacob, Ana Paula Correa, Fernanda do Nascimento Maia, Dafne Dain Gandelman Horovitz, Carla Trevisan Martins Ribeiro

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019421

The Impact of Accountable Care Units on Patient Outcomes

David H. Howard, Susan E. Shapiro, David J. Murphy, Elizabeth C. Overton, Liam Chadwick and Jason M. Stein

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019414

Expectations and Attitudes Regarding Chronic Pain Control: An Exploration Using Mind Genomics

Gillie Gabay, Attila Gere, Glenn Zemel, Danny Moskowitz, Ran Shifron and Howard Moskowitz

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019412

Admission Potassium / Sodium Ratio Linearly Predicts Mortality Outcome Following an Emergency Medical Admission

Richard Conway, Declan Byrne, Deirdre O’Riordan and Bernard Silke

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2019411

Diagnostic and Prognostic Value of Serum Cyfra 21–1 Levels in Patients with Pancreatic Cancer

Jung Hoon Kim, Young Chul Yoon, Joon Cheol Song, Jeong Won Jang and In Sook Woo

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018342

Global Healthcare Workers Migration: A Human Resource Management Concern

James Ducey and Satesh Bidaisee

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018335

Cross-sectional Study Investigating Texting and Driving in Grenada, West Indies

James A Ducey, Ryan Malave, Iman Zahedi, Emmanual Keku and Satesh Bidaisee

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018334

Low levels of HDL-cholesterol and endothelial dysfunction: a systematic review and meta-analysis

Leonardo Roever, MHS, Elmiro Santos Resende, PhD, Angélica Lemos Debs Diniz, PhD, Nilson Penha-Silva, PhD, João Lucas O’Connell, PhD, Fernanda Rodrigues de Souza, PhD, Poliana Rodrigues Alves Duarte, PhD, Paulo Fernando Silva Gomes, MD, Américo José Caixeta Neto, Lívia Maria Ambrósio da Silva, Rosangela de Oliveira Felice, Hugo Ribeiro Zanetti, MSc, Anaisa Silva Roerver-Borges, MD, Fernando César Veloso, MHS, Thiago Montes Fidale, PhD, Antonio Casella-Filho, PhD, Paulo Magno Martins Dourado, PhD, Antonio Carlos Palandri Chagas, MD, PhD, Sadeq Ali-Hasan-Al-Saegh, MD, Paulo Eduardo Ocke Reis, PhD, Rogério de MeloCosta Pinto, PhD, Gustavo B. F. Oliveira, PhD, Álvaro Avezum, PhD, Mansueto Neto, PhD, André Durães, PhD, Rose Mary Ferreira Lisboa da Silva, PhD, Antonio José Grande, PhD, CeliseDenardi, MD, Renato Delascio Lopes MD, PhD, NiteshNerlekar, MD, Shahab Alizadeh, MSc, Adrian V. Hernandez, MD, PhD, Maria Inês da Rosa, MD, PhD, Gary Tse, MD, PhD, Tong Liu, MD, PhD, Giuseppe Biondi-Zoccai, MD, MStat

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018333

A Possible Role for Midkine in the Pathogenesis of Behçet’s Syndrome

A. Şükrü Aynacıoğlu, Ayhan Bilir, and M. Yakup Tuna

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018323

Gerhard Domagk (1895-1964) and the Origin of Anti- Bacterial Therapy

Ronald P. Rubin

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018322

Retrospective Study of 133 Canadian Hidradenitis Suppurativa Patients and Literature Review

Erika L. Crowley, Claudia J. Posso-De Los Rios, Melinda J. Gooderham

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018321

Targeting of the Wnt/β-Catenin Pathway in Chronic Lymphocytic Leukaemia may adversely affect CTLA-4 expression and function

Gary Lynch, Paul Kennedy, Stephen Bergin, Siobhan Glavey, Philip W Murphy, John Quinn, and Philip T Murphy

Short Report – Internal Med Res Open J

DOI: 10.31038/IMROJ.2018311

Infection Trend, Distribution, and Factors Associated with Hepatitis B Virus Infection in Delaware, 2005-2015

Nhiem Viet Luong, Mamadou Diallo, Laura Gannon, Martin Luta and Awele Maduka-Ezeh

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017232

Surrogate Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC)

Monika Szydlowska-Jakimiuk, Joanna Raszeja-Wyszomirska

Research Articles – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017231

Identification Potency of Clinical Isolates in Aspergillus Species Using MALDI-TOF MS

Norihito Tarumoto, Jun Sakai, Keisuke Sujino, Takuya Maeda, Mayu Ohta, Toshiyuki Yamaguchi, Takashi Murakami, Hideaki Ohno and Shigefumi Maesaki

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017223

Reaching Beyond Patient-Centered Medical Home Walls: A Mixed-Methods Evaluation of A Community Health Team Intervention

Sklar M, Coleman M, Campbell S, Yeracaris P, Hurwitz D, Hewitt S, Fortin EW and Goldman RE

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017222

Field Deployment of Loop-Mediated Isothermal Amplification for Centralized Mass-Screening of Asymptomatic Malaria in Zanzibar: A Pre-Elimination Setting

Ulrika Morris, Mwinyi Khamis, Berit Aydin-Schmidt, Ali K Abass, Mwinyi I Msellem, et al.

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017221

Is Intravenous Iron Treatment a Risk for Infection?

Emilio Fábrega, María José García, Carmen Alonso, Manuel Fernandez-Miera, et al.

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017214

Humanized Monoclonal Antibodies in Pulmonology: An Integrated Review

Arzu DidemYalcin, Kevser Onbasi, RusenUzun, Felix Herth, Philipp Albert Schnabel

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017213

Basic Food Safety Practise of Open-Air-Market Vending In The Eastern Highlands Of Papua New Guinea

Johnson Makaen, Tobias Maure and Sauli Bebes

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2017211

H Pylori Infection as Risk Factor for GIT Bleeding in Haemophilic Patients

Noha M El Husseiny, Louis Essac and Mona Al Kassas

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016126

Surgical Reduction of Visceral versus Subcutaneous Fat and Effect on Features of the Metabolic Syndrome

Mahmoud Abdelaal, Carel W le Roux and Neil G Docherty

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016125

Restraint Use in the Management of the Elderly with Dementia in Hospital

Lim SC, Poon WH

Review Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016124

Re-igniting the PE debate

Avinash Aujayeb, Joseph Mackenzie

Case Report – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016123

Evidence-Based Medicine (EBM) and Clinical Practice

Luigi Pagliaro

Editorial – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016122

Developing Nutrition Awareness in First Year Medical Students

Bruckner Geza, Elder William and Sehnert Scott

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016116

Discussing Why Hemochromatosis Is Ignored

Rostern Tembo

Research Article – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016114

Ileum Ulcer Bleeding By Cytomegalovirus Infection In A Colon Cancer Patient

Hui-Chun Chao, Khee-Siang Chan and Wen-Liang Yu

Case Report – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016112

Congenital Hypercoagulable Disorders

Federico Cacciapuoti

Editorial – Internal Med Res Open J

DOI: 10.31038/IMROJ.2016111

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