Journal of Clinical Research and Medicine (ISSN: 2769-4275)

Journal of Clinical Research and Medicine (ISSN: 2769-4275)

Welcome to Journal of Clinical Research and Medicine- an international, peer-reviewed open access and bimonthly journal that concentrates on general medical research and clinical practice. published in English. The Journal aims at publishing experimental, translational and practice at the point of care studies through evidence-based, scientifically written articles from different disciplines of healthcare research in the form of original Research Article, Editorial, Review Article, Rapid Communication, Case Report, Short Communications, Conference Proceedings, Special Issue Article, Mini Review, Annual Meeting Abstract, Letters, and Observations with analysis and discussion.

Journal scope: All disciplines of clinical medicine, medical research and clinical practice, preventive medicine, epidemiology, nursing, and healthcare research, clinically focused, evidence-based medicine.

Our International Expert Editorial Committee actively pursues to be a premier for the dissemination of knowledge through advocating excellence in research and improving the clinical practice outcomes in healthcare.

JCRM is committed to providing its readers with relevant, rigorously peer reviewed, original scientific medical research that substantially improves human health and well-being and give readers access to multi-disciplinary sources for continuing medical education in basic and clinical sciences that enhance informed clinical decision-making.

You are welcome to submit your work to submissions@researchopenworld.com

Open Access Policy: This journal is an open access journal which provides immediate, worldwide, boundary free access to the full content of every distributed article without charging readers or their institutions for access. Readers are given authorization to read, circulate, copy, print, download, search, or link to the full texts of all articles in JCRM.

Editorial Board

Our Esteemed Editorial Board Members

Hafiz Suleria

Department of Food, Nutrition, Dietetics and Health,
Kansas State University,
USA


Errani Costantino

Department of Musculoskeletal Oncology ,
Rizzoli Orthopedic Institute,
Italy


Lais H Osmani

Division of Hematopathology,
Department of Pathology,
Johns Hopkins HospitaL,
USA


Al Giwa

Department of Emergency Medicine,
Icahn School of Medicine at Mount Sinai,
USA


Katrin Schenk

Department of Physics,
Randolph College,
USA


Ronald B Natale

Department of Medicine,
Division Hematology/Oncology,
Samuel Oschin Comprehensive Cancer Institute,
Cedars-Sinai Medical Center,
USA

Yasuo Iwasaki

Department of Neurology,
Toho University Omori Hospital,
Japan


Tadamitsu Kishimoto

Immunology Frontier Research Center (IFReC),
Osaka University,
Japan


Ronald B. Natale

Division of Hematology/Oncology,
Samuel Oschin Comprehensive Cancer Institute,
Cedars-Sinai Medical Center,
USA


Naohiko Ueno

Kagoshima University Graduate School of Medical and Dental Sciences,
Japan


Junya Sato

Department of pharmacy,
Shizuoka Cancer Center,
Japan


Dr. Jia Liu

Division of Endocrinology and Metabolism
Department of Medicine
University of Virginia Health System
Charlottesville, VA
USA

Shigeo Masuda

Department of Cardiovascular Surgery (Sawa Lab),
Osaka University Graduate School of Medicine,
Japan


Atsushi Saito

Department of Neurosurgery,
Sendai Medical Center,
Japan


Anna La Salvia

Department of Medical Oncology,
San Luigi Gonzaga Hospital,
University of Turin,
Italy


Takaki Ishikawa

Department of Legal Medicine,
Osaka City University Medical School,
Japan


Yuusaku Sugihara

Department of General Medicine,
Okayama University Medical School,
Japan


Published Articles

COVID-19 Vaccine Hesitancy among Syrian Refugees

Sarah Sabrine Kilic, Mehmet Celal Kizilkaya, Ceren Atalar, Deniz Oncel, Mehmet Abdussamet Bozkurt, et al.

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2023611

Astrocyte, Lipid Metabolism in Alzheimer’s Disease and Glioblastoma

Xu Zhang, Ping Lu and Xiaorong Shen

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2022555

Hypothalmic Hamartoma – A Rare Cause of Central Precocious Puberty

Rida Zainab, Syeda Baneen Fatima, Ramsha Fatima, Imtiaz Ali, Bushra Shamim and Bhagwan Das

Case Report – J Clin Res Med

DOI: 10.31038/JCRM.2022553

Cytoplasm, Cytosol and Cytoskeleton

Ufaque Batool K. Samo, Kausar Abbas Saldera, Shafaque Batool, Reema Samo, Abdul Raheem Tunio and Raheela Mangi

Review Article – J Clin Res Med

DOI: 10.31038/JCRM.2022552

Arizona Reopening Phase 3 and COVID-19: After 18 Months

Howard J Eng MS, DrPH, RPh

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2022544

Effects of Abexol (D-002): A Mixture of Beeswax Alcohols, on Joint Discomforting Symptoms in Healthy Volunteers

Roberto Puente Rodríguez, Julio César Fernández Travieso, Sarahí Mendoza Castaño, José Illnait Ferrer, Meilis Mesa Angarica, et al.

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2022543

A Case of White Matter Hyperintensities in the Brain

Sangaran Gopal, Shanthi Mariapan, Ruchi Negi, Saiful and Bernardine Macrina

Case Report – J Clin Res Med

DOI: 10.31038/JCRM.2022542

A Living System

Martin Vlcek

Perspective Article – J Clin Res Med

DOI: 10.31038/JCRM.2022541

Supporting Hospital Efficiency at the Community Level

Ronald Lagoe and Shelly Littau

Short Article – J Clin Res Med

DOI: 10.31038/JCRM.2022523

Incidence of COVID-19 Infection in Advanced Lung Cancer Patients Treated with Chemotherapy and or Immunotherapy

Carmelo Tibaldi, Alice Lunghi, Ilaria F Furfaro, Giacomo Allegrini and Editta Baldini

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2022522

COVID 19 Impact on Medical Students in Jordan, Cross-Sectional, Prospective Study

Ehab Abu Marar MD, Basel Elayan MD, Amer Sindiani MD, Subhi Al-Issawi MD, Sohaib Al-Omary MD and Mohamed Elfarra MD

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2022514

The Effect of Prosody and Its Suprasegmentals on Voice Production

Natalie Schaeffer, Simeon Blitman and Akiko Fuse

Review Article – J Clin Res Med

DOI: 10.31038/JCRM.2022512

Arizona Reopening Phase 3 and COVID-19: One Year Later

Howard J Eng MS, DrPH, RPh

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2022511

Incobotulinumtoxin Diluted in Zinc Gluconate Solution for Facial Wrinkles: Randomized Clinical Trial

Leonardo Oliveira Ferreira Bianquini, Paula Força Dellacqua, Lúcia Helena Sagrillo Pimassoni, and Denise Cantarelli Machado Machado

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2021414

Travelers’ Diarrhea in the Era of COVID-19

Amanda Radulescu

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2021413

Clinical and Microbiological Outcomes of Er:YAG Laser Used as an Adjunct in Non-Surgical Periodontal Therapy: A Randomized Clinical Trial

Abiar Alwael, Isaac Kim, Bjorn Steffensen, Charles Hawley, Guzin Uzel, Nadeem Karimbux, Sarah Pagni and Robert Gyurko

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2021412

A Retrospective Comparison of the Modified Kakita Method and the Modified Cattel-Warren Anastomosis

Fumiyoshi Saito, Kenichiro Araki, Norio Kubo, Akira Watanabe, Mariko Tsukagoshi, Norihiro Ishii, Ken Shirabe and Hiroyuki Kuwano

Original Article – J Clin Res Med

DOI: 10.31038/JCRM.2020345

Initial Experience with the SCHWIND ATOS and SmartSight Lenticule Extraction

Kishore Raj Pradhan and Samuel Arba Mosquera

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2020343

Liver Stiffness Using Transient Elastography Predicts Worse Survival in Patients with Chronic Heart Failure

Yasuyuki Tamai, Katsuya Shiraki, Kazushi Sugimoto, Kaoru Dohi and Yoshiyuki Takei

Original Article – J Clin Res Med

DOI: 10.31038/JCRM.2020341

Optimizing Patient Specific Medication Cassette Accuracy

Maria Paiva and Cathal Murphy

Research ArticleJ Clin Res Med

DOI: 10.31038/JCRM.2020334

Discharge Dilemma: COVID 19 Positive Patients from Hospital

Shaikh S, Sandhu ZA and James C

Review ArticleJ Clin Res Med

DOI: 10.31038/JCRM.2020333

A Promising Alternative to Temporal Artery Biopsy for GCA

Sandhu Z, Shaikh S and Reardon M

Case ReportJ Clin Res Med

DOI: 10.31038/JCRM.2020332

Controlled Clinical Trial on Effect of ‘Carica Papaya’ Leaf Extract on Patients with Dengue Fever

Sanath Hettige, Jagath Pushpakumara, Lagath Udara Wanigabadu, Eliyapurage Minaka Ransirini Hettige, Arosha Kottege, Jayaratne SD and Gunathilake Saman

Research ArticleJ Clin Res Med

DOI: 10.31038/JCRM.2020331

Telemedicine: Enabling Patients with Arrhythmias in Self-Care Behaviors

Kathleen Fasing DNP-c, MS, ACNP, Patricia Clark BSN, MSN, DNP, Rachel Mahas Phd, MS, MPH, Vicki Ashker DNP, RN CCRN and Hakan Oral MD

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2020326

The Northwestern Abdominoplasty Model – A novel human scar model

Ji-Cheng Hsieh, BA, Chitang J. Joshi, MBBS MS, Rou Wan, MD, Robert D. Galiano, MD, FACS

EditorialJ Clin Res Med

DOI: 10.31038/JCRM.2020323

Driving Patient Engagement in Exercise Oncology: A Patient’s Journey through Maple Tree Cancer Alliance

Karen Y. Wonders, Ph.D., FACSM, Nicholas Foggia, & Rob Wise

Research ArticleJ Clin Res Med

DOI: 10.31038/JCRM.2020322

Current Treatment of Traditional Chinese Medicine for Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Our Research

Gao Qinghe, Liu Shengjing, Du Guanchao, Fu Jianhua, Guo Jun

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2020314

Clinical Evidence on Apatinib in Treating Chemotherapy-Refractory Metastatic Esophageal Squamous Cell Carcinoma

Ying Liu, Chengliang Yang, Shuning Xu, Leiming Guo, Lei Qiao, Xiaoyuan Wu, Chunyu He, Ke Li

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2020313

Measurement and Clinical Significance of Novel Inflammatory Biomarkers in Patients with Psoriasis and Cardiovascular Risk Factors for the Primary Care Practitioner

Carmen Rodríguez-Cerdeira, Erick Martínez -Herrera, Miguel Carnero-Gregorio, Adriana López-Barcenas, Mónica Cordeiro-Rodríguez, Gabriella Fabbrocini, Ardiana Sinani, Brunilda Bardhi, José Luís González-Cespón

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2020312

Collision Tumor of a Squamous Cell Carcinoma and Adenoid Cystic Carcinoma in Mobile Tongue

Xiaoyan Liao, MD, PhD, Joel B. Fontanarosa, MD, PhD, Dongwei Zhang, MD, PhD

Case Report – J Clin Res Med

DOI: 10.31038/JCRM.2020311

Presurgical MRSA Screening and Subsequent Decolonization in Elective Instrumented Neurosurgery: A Case Descriptive Study

Vincent De La Porte, Veroniek Saegeman, Elise Willems, Charlotte Stolte and Erik Van de Kelft

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019254

Acceptability and Accuracy of Cervical Cancer Screening Using a Self-Collected Veil for HPV DNA Testing by Multiplex Real-Time PCR among Adult Women in sub- Saharan Africa

Zita Aleyo Nodjikouambaye, Damtheou Sadjoli, Ralph-Sydney Mboumba Bouassa, Hélène Péré, David Veyer, Chatté Adawaye, Leman Robin, Serge Tonen-Wolyec, Moll Mahamat Tcheguena, Ali Mahamat Moussa, Donato Koyalta and Laurent Belec

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019253

Novel Pathology-Related Hub Genes in Focal Segmental Glomerulosclerosis

Qianhong Ma, Dongmei Zhang and Zhongying Huang

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019252

Cartography of Doctor-Patient Relationship: A Mind- Genomics Exploratory Study about the Public’s Response to Patient-Centered-Care

Gillie Gabay, Ido Garbi, Glenn Zemel Glenn Zemel, Attila Gere, Sharon Starke and Howard Moskowitz

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019251

Sensory Stimulation and Bradykinesia Aponeurotic Stimulation Effects on Parkinson Bradykinesia

Ana Bengoetxea, Leslie Rigal, Françoise Leurs, Guy Cheron

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019244

Promoting Medication-Adherence by Uncovering Patient’s Mindsets and Adjusting Clinician-Patient Communication to Mindsets: A Mind Genomics Cartography

Gillie Gabay, Attila Gere, Robert Sherman, Glenn Zemel, Daniel Moskowitz and Howard Moskowitz

Review Article – J Clin Res Med

DOI: 10.31038/JCRM.2019243

Symptomatic Effects of Chest Physiotherapy with Increased Exhalation Technique in Outpatient Care for Infant Bronchiolitis: A Multicentre, Randomised, Controlled Study. Bronkilib 2

S. Sebban, D. Evenou, C. Jung, C. Fausser, S. JC. Jeulin, S. Durand, M. Bibal, V. Geninasca, M. Saux, M. Leclerc

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019242

A rare case of distant metastasis of primary malign pericardial mesothelioma with 18F-FDG PET/CT

Tarik Sengoz, Nilufer Avci, Ezgi Basak Erdogan, Erdogan Bulbul

Case Report – J Clin Res Med

DOI: 10.31038/JCRM.2019234

The Effects of Nicardipine on the Onset Time and Intubating Conditions of Cisatracurium

Pornwicha Chumak, M.D., Sahawat Thertchanakun, M.D., Wirat Wasinwong, M.D., Prae Plansangkate, M.D., Sasithorn Mahatthanathporn, Amphan Chantarokorn

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019233

Ultrasound Localization of Intercostal Perforating Vessels Reduces Skin Necrosis Complications from Nipple-Sparing Mastectomy

Robert Maganini, MD, FACS, Anthony Maganini, Richard Maganini

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019232

Severe acute respiratory infection and viral infections in adult patients: active surveillance results

Sonia M Raboni, Bernardo M Almeida, Nicholas Setter, Marco L Peres

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019231

LDL and beyond: New emerging LDL biomarkers in lipidology

Dr. Sikandar Hayat Khan

Short Communication – J Clin Res Med

DOI: 10.31038/JCRM.2019225

Mediastinal Mass in a Brain Tumor Patient Treated with Chemotherapy: Lymphoma after Temozolomide

Austin Dixon, MD, MBA, Bennett Chin, MD, Matthew McKinney, MD

Case Report – J Clin Res Med

DOI: 10.31038/JCRM.2019224

Association Between Age and Short-Term Patient Reported Pain Scores After Complex Spinal Fusion for Adult Deformity Correction: Is Perception of Pain Different?

Aladine A. Elsamadicy M.D., Megan Lee, B.S., Andrew Koo B.S., Adam J. Kundishora M.D., Joaquin Camara-Quintana M.D., Tariq Qureshi MBBS, MBA, Luis Kolb M.D., Maxwell Laurans, M.D., M.B.A., Khalid Abbed M.D., Isaac O. Karikari M.D.

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019223

EUS in the Management of High-Risk Gastrointestinal Precancerous Lesions before Endoscopic Resection

Yanliu Chu M.D., Ph.D, Ranran Wang, Tian Li, Xiuli Qiao, Xiaofeng Wang, Feng Liu, Xiaozhong Gao, Songyang Yu

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019222

Long-Term Effect of a Short Sucrose/Xylitol Exposure on Survival of Permanent Teeth: A Practice-Based Study

Päkkilä J, Hangasmaa H, Halunen I, Laitala M-L, Anttonen V

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2019221

Effect of Perilla Oil on Reducing Arteriosclerosis Risk: A Randomized Controlled Cross-Over Study

Erena Tokudome, Masakazu Imamura, Sayaka Shiomitsu, Ryoko Miyanohara, Emiko Hori, Hiroto Nishimata, Takuma Yoshinaga

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018144

Clinical diversity of Low Carbohydrate Diet (LCD)

Hiroshi Bando, MD, PhD

Commentary – J Clin Res Med

DOI: 10.31038/JCRM.2018142

Per oral vitamin B12 replacement therapy after gastrectomy and its optimal dose; retrospective study

Yasushi Rino, Takanobu Yamada, Toru Aoyama, Masakatsu Numata, Haruhiko Cho, Takashi Oshima, Tsutomu Sato, Soichiro Morinaga, Manabu Shiozawa, Takaki Yoshikawa, Norio Yukawa, Munetaka Masuda

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018141

Effect of a Traditional Chinese Medicine combined therapy on Spleen-Qi deficiency HIV/AIDS patients: a randomized controlled trial

Ying Liu, Meng Sun, Kelin Wang, Gang Sun, Xiaohong Wang, Zhiguang Zhai, Peizhu Sun, Jian Wang

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018135

Aqueduct-100, A New Device and Method for Controllable Cervical Dilation

Larry Spiegelman, MD, Ramon Sanchez-Rauder MD, and Cristina Travieso ARNP

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018134

Observational Study to Assess the Safety and Clinical Effectiveness of the Hospital Universitario de Canarias Massive Transfusion Protocol

González Fariña V, Martín Lorenzo MC, Borges Jurado R, Jiménez Rivera J, Raya Sánchez JM, Brouard MT, Arribas-Carrión JC, Montón Giménez N

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018133

Long-Term Outcomes in Patients after Discontinuation of Immune Checkpoint Inhibitors

Zin W. Myint, Ruta Arays, Arun K. Arumugam Raajasekar, Peng Wang

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018132

Proseal™ LMA Insertion: Comparison of the Nasogastric Catheter Guided Technique with the Conventional Digital Technique

Wirat Wasinwong, M.D., Thanapol Tosakparalerd, M.D., Sunisa Chatmongkolchat, M.D., Pannipa Phakam, B.N.S., Jamras Na-Klongdee, B.N.S.

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018131

An NT5E Gene Polymorphism Associates with Low Bone Mineral Density in Chronic Kidney Disease Patients

Richella Ryan PhD, Sarah Cleary BSc, Kevin O’Shaughnessy FRCP, Yasmin PhD

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018125

Novel Case of 9p- Deletion in a Patient with Cardiac Pathology and a Review of the Literature

Koslow E, Reeves PT, Anchan, J, Rohena L

Review Article –J Clin Res Med

DOI: 10.31038/JCRM.2018124

General Practitioners’ Current and Emerging Views about Pay for Performance Schemes

Giorgia Rotundo, Marianna Mauro and Monica Giancotti

Review Article – J Clin Res Med

DOI: 10.31038/JCRM.2018122

Therapeutic Modalities for Management of Hemolysis in Pediatric Extracorporeal Membrane Oxygenation (ECMO)

Aqsa Shakoor, Ariela Zenilman, Jennifer DeFazio, Linda Li, Cindy Neunert, Angela Kadenhe-Chiweshe

Mini Review – J Clin Res Med

DOI: 10.31038/JCRM.2018121

Validity of Lithuanian Version of the Child Perceptions Questionnaire Among Adolescents up to the Ages of 18

Aistė Kavaliauskienė, Antanas Šidlauskas and Apolinaras Zaborskis

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018113

Intravitreal Injections of Melanocortin Receptor 1, 5 Agonists Prevents Neovascularization in a VEGF165 Mouse Model of Retinopathy

Rosa Maisto, Maria Consiglia Trotta, Settimio Rossi, Carlo Gesualdo, Dario Siniscalco, Franca Ferraraccio, Jorge Miquel Barcia, Francesca Simonelli, Clara Di Filippo, and Michele D’Amico

Research Article – J Clin Res Med

DOI: 10.31038/JCRM.2018112

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